منابع مشابه
Genome Annotation without Genes
The concept of the gene plays a fundamental role both in the interpretation and in the organization and storage of molecular biology data. Genes are treated as if they were unambiguously characterized physical entities with clearly defined measurable properties. The ubiquitous usage of genes in current bio-databases reinforces this perception. A closer look at the data models and the ongoing di...
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UNLABELLED AMIGene (Annotation of MIcrobial Genes) is an application for automatically identifying the most likely coding sequences (CDSs) in a large contig or a complete bacterial genome sequence. The first step in AMIGene is dedicated to the construction of Markov models that fit the input genomic data (i.e. the gene model), followed by the combination of well-known gene-finding methods and a...
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This chapter introduces the use of Text Mining in scientific literature for biological research, with a special focus on automatic gene and protein annotation. This field became recently a major topic in Bioinformatics, motivated by the opportunity brought by tapping the BioLiterature with automatic text processing software. The chapter describes the main approaches adopted and analyzes systems...
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This paper proposes a fast and automatic functional annotation method for hundreds of unannotated genes in biological databases. Genes are often described and discussed in biomedical literature that can be used to unravel the functions of genes. We have proposed a reliable text mining approach to discover functional annotations for genes from literature. This approach was validated by building ...
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The purpose of this 6-week project is the fine scale regulatory annotation of a list of genes that have been specifically shown to be active in tumour (cancer) cells – we will refer to these as “cancer” genes. Understanding under what circumstances these genes get turned on, that is, what factors regulate the transcription of cancer genes is of utmost importance in cancer research. Bioinformati...
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ژورنال
عنوان ژورنال: Plasmid
سال: 2017
ISSN: 0147-619X
DOI: 10.1016/j.plasmid.2017.03.006